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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of centrosome duplication
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Accession:GO:0010824 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

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regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEP131 centrosomal protein 131 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:73,138,784...73,172,677
Ensembl chr16:73,139,683...73,170,339 		JBrowse link
G CHMP1A charged multivesicular body protein 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:74,990,706...75,002,074
Ensembl chr 5:74,990,410...75,001,988 		JBrowse link
G CHMP1B charged multivesicular body protein 1B involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chr18:69,534,547...69,539,377 JBrowse link
G CHMP2A charged multivesicular body protein 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:50,827,200...50,830,730
Ensembl chr 6:50,827,284...50,830,702 		JBrowse link
G CHMP2B charged multivesicular body protein 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:89,672,043...89,701,801
Ensembl chr22:89,672,022...89,701,897 		JBrowse link
G CHMP3 charged multivesicular body protein 3 involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chr14:20,536,490...20,654,761
Ensembl chr14:20,594,817...20,654,404 		JBrowse link
G CHMP4B charged multivesicular body protein 4B involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chr 2:38,093,909...38,139,932
Ensembl chr 2:38,093,829...38,140,367 		JBrowse link
G CHMP4C charged multivesicular body protein 4C involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chr 8:77,143,302...77,174,874
Ensembl chr 8:77,143,612...77,173,852 		JBrowse link
G CHMP5 charged multivesicular body protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:46,989,349...47,006,035
Ensembl chr12:46,988,340...47,006,742 		JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:81,326,464...81,350,640
Ensembl chr 1:81,328,422...81,350,214 		JBrowse link
G FBXW5 F-box and WD repeat domain containing 5 involved_in ISO (PMID:21725316) UniProt PMID:21725316 NCBI chr12:1,246,416...1,250,930
Ensembl chr12:1,246,702...1,252,688 		JBrowse link
G GEN1 GEN1 Holliday junction 5' flap endonuclease involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:89,886,102...89,917,485
Ensembl chr14:89,888,853...89,911,293 		JBrowse link
G NAT10 N-acetyltransferase 10 involved_in ISO (PMID:31722219) UniProt PMID:31722219 NCBI chr 1:31,126,387...31,171,751
Ensembl chr 1:31,126,262...31,170,833 		JBrowse link
G NPM1 nucleophosmin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16007073) TreeGrafter
MGI		 PMID:16007073 GO_REF:0000118 NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925 		JBrowse link
G PDCD6IP programmed cell death 6 interacting protein involved_in ISO (PMID:20616062) UniProt PMID:20616062 NCBI chr15:78,265,099...78,339,307
Ensembl chr15:78,265,252...78,339,873 		JBrowse link
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in ISO (PMID:20554582) UniProt PMID:20554582 NCBI chr17:20,411,746...20,873,601 JBrowse link
G PKHD1 PKHD1 ciliary IPT domain containing fibrocystin/polyductin involved_in IEA Ensembl GO_REF:0000107 Ensembl chr17:20,455,917...20,876,907 JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867 		JBrowse link
G VPS4B vacuolar protein sorting 4 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:16,336,959...16,370,208
Ensembl chr18:16,336,921...16,370,291 		JBrowse link
G XPO1 exportin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16297385) Ensembl
MGI		 PMID:16297385 GO_REF:0000107 NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:81,627,911...81,641,598
Ensembl chr24:81,630,099...81,641,218 		JBrowse link
negative regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDK5RAP2 CDK5 regulatory subunit associated protein 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:18,999,203...19,186,801
Ensembl chr12:18,999,213...19,186,785 		JBrowse link
G KAT2A lysine acetyltransferase 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:64,146,146...64,154,726
Ensembl chr16:64,146,207...64,154,252 		JBrowse link
G KAT2B lysine acetyltransferase 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,769,590...64,885,536
Ensembl chr15:64,770,185...64,886,219 		JBrowse link
G MDM1 Mdm1 nuclear protein involved_in IEA InterPro GO_REF:0000002 NCBI chr11:63,926,950...64,082,149
Ensembl chr11:63,927,640...63,965,097 		JBrowse link
G TRIM37 tripartite motif containing 37 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:34,310,090...34,446,887
Ensembl chr16:34,310,159...34,436,177 		JBrowse link
negative regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCNF cyclin F involved_in
acts_upstream_of_or_within		 ISO (PMID:20596027) UniProt
MGI		 PMID:20596027 NCBI chr 5:2,302,249...2,336,188
Ensembl chr 5:2,302,341...2,335,270 		JBrowse link
G CENATAC centrosomal AT-AC splicing factor involved_in ISO (PMID:31722219)
(PMID:34009673)		 UniProt PMID:31722219 PMID:34009673 NCBI chr 1:110,371,873...110,386,921 JBrowse link
G NPM1 nucleophosmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925 		JBrowse link
G NUBP1 NUBP iron-sulfur cluster assembly factor 1, cytosolic involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16638812), (PMID:23028652) Ensembl
MGI		 PMID:16638812 PMID:23028652 GO_REF:0000107 NCBI chr 5:10,224,965...10,248,328
Ensembl chr 5:10,225,173...10,249,047 		JBrowse link
G TMEM67 transmembrane protein 67 involved_in ISO
IEA		 RGD
Ensembl		 PMID:19515853 GO_REF:0000107 RGD:8554306 NCBI chr 8:88,726,783...88,818,111
Ensembl chr 8:88,726,837...88,792,049 		JBrowse link
positive regulation of centriole elongation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPJ centromere protein J involved_in ISO (PMID:27185865) UniProt PMID:27185865 NCBI chr 3:4,319,136...4,360,214
Ensembl chr 3:4,319,103...4,360,158 		JBrowse link
G CEP120 centrosomal protein 120 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:26,392,940...26,469,818
Ensembl chr23:26,392,941...26,469,717 		JBrowse link
G CEP295 centrosomal protein 295 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:84,911,256...84,982,396
Ensembl chr 1:84,916,192...84,982,296 		JBrowse link
G PPP1R35 protein phosphatase 1 regulatory subunit 35 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:12,768,645...12,770,273
Ensembl chr28:12,768,642...12,770,329 		JBrowse link
G VPS4B vacuolar protein sorting 4 homolog B involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:16,336,959...16,370,208
Ensembl chr18:16,336,921...16,370,291 		JBrowse link
positive regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPJ centromere protein J involved_in ISO (PMID:22020124) ComplexPortal PMID:22020124 NCBI chr 3:4,319,136...4,360,214
Ensembl chr 3:4,319,103...4,360,158 		JBrowse link
G NUP62 nucleoporin 62 involved_in ISO (PMID:24107630) UniProt PMID:24107630 NCBI chr 6:43,063,483...43,086,264
Ensembl chr 6:43,064,875...43,066,440 		JBrowse link
G PLK4 polo like kinase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22349705) MGI
Ensembl		 PMID:22349705 GO_REF:0000107 NCBI chr 7:75,005,468...75,023,768
Ensembl chr 7:75,006,431...75,023,730 		JBrowse link
G SASS6 SAS-6 centriolar assembly protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,205,538...33,254,292
Ensembl chr20:33,205,742...33,257,170 		JBrowse link
G STIL STIL centriolar assembly protein involved_in ISO (PMID:22020124) ComplexPortal PMID:22020124 NCBI chr20:85,600,171...85,662,732
Ensembl chr20:85,604,539...85,662,333 		JBrowse link
positive regulation of centrosome duplication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AZIN1 antizyme inhibitor 1 ISO RGD PMID:17667942 RGD:14700805 NCBI chr 8:97,679,775...97,717,486
Ensembl chr 8:97,679,468...97,696,928 		JBrowse link
G CEP120 centrosomal protein 120 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:26,392,940...26,469,818
Ensembl chr23:26,392,941...26,469,717 		JBrowse link
G CEP295 centrosomal protein 295 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:84,911,256...84,982,396
Ensembl chr 1:84,916,192...84,982,296 		JBrowse link
G NPM1 nucleophosmin 1 acts_upstream_of_or_within ISO (PMID:17015463) MGI PMID:17015463 NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925 		JBrowse link
G POC1A POC1 centriolar protein A acts_upstream_of_or_within ISO (PMID:26496357) MGI PMID:26496357 NCBI chr22:13,442,516...13,549,290
Ensembl chr22:13,442,368...13,520,345 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17015463) InterPro
MGI		 PMID:17015463 GO_REF:0000002 NCBI chr14:96,275,889...96,443,048
Ensembl chr14:96,276,023...96,432,790 		JBrowse link
regulation of centriole replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CENPJ centromere protein J involved_in ISO (PMID:20531387) UniProt PMID:20531387 NCBI chr 3:4,319,136...4,360,214
Ensembl chr 3:4,319,103...4,360,158 		JBrowse link
G CEP76 centrosomal protein 76 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:71,192,753...71,221,909
Ensembl chr18:71,192,568...71,221,790 		JBrowse link
G NPM1 nucleophosmin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:73,555,020...73,575,910
Ensembl chr23:73,555,260...73,575,925 		JBrowse link
G PLK2 polo like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:54,629,868...54,636,134
Ensembl chr 4:54,629,194...54,636,032 		JBrowse link
G SPICE1 spindle and centriole associated protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:67,347,738...67,413,403
Ensembl chr22:67,355,716...67,412,729 		JBrowse link
G STIL STIL centriolar assembly protein involved_in ISO (PMID:22020124) UniProt PMID:22020124 NCBI chr20:85,600,171...85,662,732
Ensembl chr20:85,604,539...85,662,333 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    cellular process 15887
      cell cycle process 1306
        centrosome duplication 74
          regulation of centrosome duplication 44
            negative regulation of centrosome duplication + 10
            positive regulation of centrosome duplication 6
            regulation of centriole replication + 18
Path 2
Term Annotations click to browse term
  biological_process 16925
    cellular process 15887
      cellular component organization or biogenesis 6765
        cellular component organization 6524
          organelle organization 3662
            cytoskeleton organization 1524
              microtubule cytoskeleton organization 684
                microtubule organizing center organization 152
                  centrosome cycle 139
                    regulation of centrosome cycle 50
                      regulation of centrosome duplication 44
                        negative regulation of centrosome duplication + 10
                        positive regulation of centrosome duplication 6
                        regulation of centriole replication + 18
paths to the root